本文選題：生物膜 + 病原學(xué)　； 參考：《中國(guó)微生態(tài)學(xué)雜志》2014年11期

【摘要】：目的探討機(jī)械通氣危重兒氣管導(dǎo)管細(xì)菌生物膜對(duì)提高病原菌檢出率的作用。方法選擇2013年入住新生兒科需要機(jī)械通氣的新生兒,根據(jù)機(jī)械通氣的時(shí)間將研究對(duì)象分為3組:≤72 h組、73~168 h組及168 h組,以漩渦振蕩器振蕩氣管導(dǎo)管末端,振蕩液培養(yǎng),與同時(shí)送檢的深部痰培養(yǎng)結(jié)果進(jìn)行統(tǒng)計(jì)學(xué)比較。結(jié)果在機(jī)械通氣時(shí)間≤72 h組、73~168 h組中,漩渦振蕩器振蕩液與深部痰培養(yǎng)的陽(yáng)性率高度一致,Kappa值分別為0.799、0.710,P值分別為0.000及0.000;在168 h組中,二者中度一致,Kappa值為0.651,P值為0.001。兩種方法分離的菌株以產(chǎn)ESBL酶肺炎克雷伯桿菌最多見(jiàn),產(chǎn)ESBL酶大腸桿菌次之,兩種方法間菌株的構(gòu)成及耐藥性差異無(wú)統(tǒng)計(jì)學(xué)意義。結(jié)論以漩渦振蕩器法獲取氣管導(dǎo)管細(xì)菌生物膜不能提高機(jī)械通氣患兒的病原學(xué)檢測(cè)陽(yáng)性率,對(duì)臨床用藥無(wú)明顯指導(dǎo)意義。
[Abstract]:Objective to investigate the effect of bacterial biofilm in trachea catheter on the detection rate of pathogenic bacteria in critically ill children undergoing mechanical ventilation. Methods the neonates who were admitted to the pediatric department in 2013 were divided into three groups according to the time of mechanical ventilation: group 鈮，

本文編號(hào)：2025316