本文選題：慢性心力衰竭 + 高血壓病�。� 參考：《湖北中醫(yī)藥大學學報》2018年02期

【摘要】：目的觀察心衰1號方對高血壓病、糖尿病、冠心病并發(fā)慢性心衰(陽虛水停、血瘀絡阻證)患者的臨床療效。方法將我院120例患者分成治療組和對照組,每組各60例。治療組給予西醫(yī)常規(guī)治療聯(lián)合心衰1號方治療,對照組給予西醫(yī)常規(guī)治療聯(lián)合芪藶強心膠囊治療,療程均為4周。比較兩組間紐約心臟病協(xié)會(NYHA)心功能分級、中醫(yī)證候積分、心衰體征積分、左室射血分數(shù)(LVEF)、B型腦鈉肽(BNP)、生活質(zhì)量評價、住院時間及不良反應發(fā)生率。結果對照組總有效率(73.33%)低于治療組(88.33%),差異有統(tǒng)計學意義(P0.05);與對照組比較,治療組治療后中醫(yī)證候積分、心衰體征積分較低,BNP水平較低,生活質(zhì)量評分較低,住院時間較短,差異有統(tǒng)計學意義(P0.05)。治療后,兩組LVEF均有明顯的改善(P0.05),改善程度差異無統(tǒng)計學意義(P0.05)。兩組不良反應發(fā)生率差異無統(tǒng)計學意義(P0.05)。結論心衰1號方治療高血壓病、糖尿病、冠心病并發(fā)慢性心衰(陽虛水停、血瘀絡阻證)的臨床療效較好,能夠有效改善患者心功能,改善患者臨床癥狀及生活質(zhì)量,降低BNP水平,升高左室射血分數(shù)(LVEF)水平,安全性良好。
[Abstract]:Objective to observe the clinical effect of Heart failure Formula No. 1 on patients with hypertension, diabetes and coronary heart disease complicated with chronic heart failure (Yang deficiency and water stagnation, blood stasis and collaterals obstruction). Methods 120 patients in our hospital were divided into treatment group and control group with 60 cases in each group. The treatment group was treated with routine western medicine combined with heart failure recipe No. 1, the control group was treated with traditional western medicine combined with Qiliqiangxin capsule, the course of treatment was 4 weeks. The cardiac function grading, TCM syndromes score, heart failure sign score, left ventricular ejection fraction (LVEF) B type brain natriuretic peptide (BNPP), quality of life (QOL), hospital stay and incidence of adverse reactions were compared between the two groups. Results the total effective rate of the control group (73.33) was lower than that of the treatment group (88.33%), and the difference was statistically significant (P 0.05), compared with the control group, the scores of TCM syndromes, signs of heart failure and BNP were lower, the quality of life score was lower, and the hospitalization time was shorter in the treatment group than in the control group. The difference was statistically significant (P 0.05). After treatment, LVEF in both groups was significantly improved (P 0.05), and there was no significant difference in the degree of improvement between the two groups (P 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P 0.05). Conclusion the clinical effect of Heart failure No. 1 prescription in treating hypertension, diabetes mellitus and coronary heart disease complicated with chronic heart failure (Yang deficiency and water stopping, blood stasis and collaterals blocking) is better. It can effectively improve the heart function of the patients, improve the clinical symptoms and quality of life of the patients. It is safe to reduce BNP level and increase left ventricular ejection fraction (LVEF) level.
【作者單位】： 中國中醫(yī)科學院廣安門醫(yī)院南區(qū)內(nèi)科
【基金】：北京市中醫(yī)藥科技發(fā)展資金項目(項目編號:JJ2012-01)
【分類號】：R259

【相似文獻】

相關博士學位論文 前1條

1 王吉元;心衰1號方治療高血壓病、糖尿病、冠心病并發(fā)慢性心衰的臨床研究[D];中國中醫(yī)科學院;2017年

相關碩士學位論文 前10條

1 嚴來興;辨證運用中成藥針劑對射血分數(shù)降低心衰患者心功能的影響[D];浙江中醫(yī)藥大學;2017年

2 劉美玲;2015年心內(nèi)科慢性心力衰竭中醫(yī)診療方案評價研究[D];長春中醫(yī)藥大學;2017年

3 范麗娟;桂脂益心湯配合運動康復對慢性心力衰竭（心腎陽虛、瘀水阻絡證）治療的臨床觀察[D];長春中醫(yī)藥大學;2017年

4 李亞洲;茯苓溫腎膠囊對老年冠心病慢性心力衰竭患者神經(jīng)內(nèi)分泌和相關因子的調(diào)節(jié)作用[D];安徽中醫(yī)藥大學;2017年

5 張涵;高血壓病合并焦慮抑郁的臨床調(diào)查及怡心湯干預的臨床研究[D];安徽中醫(yī)藥大學;2017年

6 夏建文;生血通便顆粒輔助治療慢性心力衰竭血瘀腸燥證的臨床研究[D];湖南中醫(yī)藥大學;2017年

7 宋鳳平;基于關聯(lián)規(guī)則高血壓病用藥規(guī)律的研究[D];山東中醫(yī)藥大學;2016年

8 田野;健心湯治療慢性心力衰竭療效觀察及對RAAS的影響[D];安徽中醫(yī)藥大學;2017年

9 元仙穎;2015年心病科高血壓病診療方案評價研究[D];長春中醫(yī)藥大學;2017年

10 劉盼利;針灸治療高血壓病的選穴規(guī)律文獻研究[D];遼寧中醫(yī)藥大學;2017年

，

本文編號：1888847