發(fā)布時(shí)間：2018-08-30 12:17

【摘要】：目的探討中國公民逝世后器官捐獻(xiàn)(Chinese donation after citizens’death,CDCD)發(fā)生腎移植功能延遲恢復(fù)(delayed graft function,DGF)的預(yù)后因素。方法回顧性分析2014年1月~2015年11月在武漢大學(xué)中南醫(yī)院138例行同種異體腎移植手術(shù)的臨床資料,21例發(fā)生DGF(DGF組),117例移植腎功能穩(wěn)定(immediate graft function,IGF)為IFG組,采用χ~2檢驗(yàn)進(jìn)行單因素分析,再用logistic模型對(duì)有統(tǒng)計(jì)學(xué)差異的因素進(jìn)行多因素分析。結(jié)果 DGF發(fā)生率為15.2%(21/138),單因素分析顯示DGF的預(yù)后因素包括受者術(shù)前血透時(shí)間≥12個(gè)月(P=0.024)、腦出血死亡供者(P=0.020)、供者血清肌酐≥177μmol/L(P=0.013)、熱缺血時(shí)間≥15 min(P=0.041)、冷缺血時(shí)間≥12 h(P=0.025)及供者經(jīng)歷心肺復(fù)蘇(P=0.001)有顯著性差異。logistic多因素分析顯示供者血清肌酐≥177μmol/L(OR=7.138,95%CI:1.418~35.937,P=0.017)、供者心肺復(fù)蘇(OR=30.207,95%CI:3.653~111.778,P=0.001)及熱缺血時(shí)間≥15 min(OR=7.762,95%CI:1.953~30.845,P=0.004)是DGF的獨(dú)立預(yù)后因素。結(jié)論供者血清肌酐≥177μmol/L、供者經(jīng)歷心肺復(fù)蘇及熱缺血時(shí)間≥15 min是導(dǎo)致CDCD發(fā)生DGF的預(yù)后因素。
[Abstract]:Objective to investigate the prognostic factors of delayed recovery of renal transplantation (delayed graft function,DGF) in (Chinese donation after citizens'death,CDCD after death of Chinese citizens. Methods from January 2014 to November 2015, we retrospectively analyzed the clinical data of 138 cases of allograft renal transplantation performed in Central South Hospital of Wuhan University (21 cases of DGF (DGF group) and 117 cases of stable renal function (immediate graft function,IGF) as IFG group. Univariate analysis was performed by 蠂 ~ 2 test. Logistic model was used to analyze the factors with statistical difference. Results the incidence of DGF was 15.2% (21 / 138). Univariate analysis showed that the prognostic factors of DGF included preoperative hemodialysis time 鈮，

本文編號(hào)：2213045