發(fā)布時間：2019-02-13 12:57

【摘要】：目的:探討Revolution CT全胃灌注掃描時間間隔對正常胃壁灌注數(shù)據(jù)的影響。方法:前瞻性分析于我院行Revolution CT腹部灌注且無胃部疾病患者28例,按臨床申請范圍不同分為連續(xù)灌注組(A組)14例,間隔灌注組(B組)14例。兩組灌注掃描均為軸掃模式,Z軸覆蓋范圍均為160 mm,A組連續(xù)采集25次,每次采集時間為2 s(曝光0.5 s,間隔1.5 s),總掃描時間50 s。B組在第15 s即采集8次后進行全腹動脈期螺旋掃描,螺旋掃描模式與軸掃模式互相轉(zhuǎn)換及掃描曝光時間12~16.2 s,再進行13次上腹軸位灌注掃描,共采集21次,總掃描時間50~54.2 s。所有圖像經(jīng)運動校正后傳至工作站進行灌注成像分析。兩名觀察者分別測量胃體部大、小彎側(cè)感興趣區(qū)的灌注參數(shù)值,包括BV、BF、MTT、TP、PEI、MSI、IRF、Tmax,統(tǒng)計各組灌注輻射劑量。使用組內(nèi)相關(guān)系數(shù)(ICC)對所得數(shù)據(jù)進行一致性檢驗,采用配對樣本t檢驗及獨立樣本t檢驗比較兩組內(nèi)及組間各灌注參數(shù)的差異。結(jié)果:兩觀察者數(shù)據(jù)測量一致性較好。兩組內(nèi)胃大彎側(cè)BV值((12.83±4.30)、(18.44±4.39)m L/(min·100 g))、BF值((61.54±10.13)、(64.99±13.77)m L/100 g)均高于小彎側(cè)BV值((9.73±3.87)、(14.28±5.40)m L/(min·100 g))、BF值((47.77±12.29)、(47.09±10.52)m L/100 g),P值分別為0.027、0.004、0.002、0.000,其余灌注參數(shù)值(MTT、TP、MSI、PEI、IRF、Tmax)差異無統(tǒng)計學(xué)意義;兩組間BV、PEI值在胃大、小彎側(cè)差異均有統(tǒng)計學(xué)意義(P=0.002、0.004、0.017、0.032),MTT及Tmax值僅在小彎側(cè)差異有統(tǒng)計學(xué)意義,在大彎側(cè)差異無統(tǒng)計學(xué)意義,且A組均低于B組,余灌注參數(shù)值(BF、TP、MSI、IRF)兩組間差異無統(tǒng)計學(xué)意義。A組劑量為14.46 m Sv,B組為12.15 m Sv,B組較A組降低15.97%。結(jié)論:Revolution CT全胃灌注掃描時間間隔對正常胃壁BV、MTT、PEI及Tmax等灌注參數(shù)有影響,但對BF、TP、MSI、IRF值無影響,且胃大、小彎側(cè)BV、BF灌注值不同。
[Abstract]:Objective: to investigate the effect of Revolution CT total gastric perfusion time interval on normal gastric wall perfusion data. Methods: 28 patients with Revolution CT abdominal perfusion without gastric diseases were prospectively analyzed. According to the clinical application range, 14 patients were divided into continuous perfusion group (group A) and septal perfusion group (group B). Two groups of perfusion scan were axial scan mode, Z axis coverage was 160 mm,A group 25 consecutive acquisition, each acquisition time was 2 s (exposure 0.5 s, interval 1.5 s),) The total scanning time was 50 s. B group underwent total abdominal arterial spiral scanning at 15 s, that is, 8 times. The spiral scan mode and axial scan mode were converted to each other and the exposure time was 12 ~ 16.2 s, and 13 axial perfusion scans were performed. A total of 21 times were collected, and the total scanning time was 50 ~ 54.2 s. All images were transmitted to workstation after motion correction for perfusion imaging analysis. The perfusion parameters of the large and small curved side of stomach were measured by two observers, including BV,BF,MTT,TP,PEI,MSI,IRF,Tmax,. Correlation coefficient (ICC) was used to test the consistency of the data. The difference of perfusion parameters between the two groups was compared by paired sample t test and independent sample t test. Results: the data of two observers were consistent. The BV value of the great curvature side of the stomach (12.83 鹵4.30), (18.44 鹵4.39) mL / (min 100 g), BF) (61.54 鹵10.13), (64.99 鹵13.77 mL / 100g) was higher than that of the small flexural side (9.73 鹵3.87). The values of (14.28 鹵5.40) mL / (min 100 g), BF) (47.77 鹵12.29), (47.09 鹵10.52) mL / 100 g), P were 0.027 鹵5.40 mL / (MTT,TP,MSI,PEI,IRF, = 0.002 鹵0.000), respectively. There was no significant difference in Tmax. There were significant differences in BV,PEI between the two groups in the large stomach and small curvature (P0. 002, 0. 004, 0. 017, 0. 032), MTT and Tmax, respectively. There was no significant difference between the two groups in the great curvature, and the difference in group A was lower than that in group B. There was no significant difference in residual perfusion parameter (BF,TP,MSI,IRF) between the two groups, but the dose of 14.46m Sv,B in group A was 12.15m Sv,B lower than that in group A (15.97m). Conclusion the interval of: Revolution CT total gastric perfusion scan has influence on BV,MTT,PEI and Tmax of normal gastric wall, but it has no effect on BF,TP,MSI,IRF value, and the BV,BF perfusion value of large and small curvature of stomach is different.
【作者單位】： 大連醫(yī)科大學(xué)附屬第一醫(yī)院放射科;
【分類號】：R816.5

【參考文獻】

相關(guān)期刊論文 前10條

1 申屠偉慧;黃品同;鄢曹鑫;潘敏強;張超;林子梅;;超聲雙重造影在進展期胃癌新輔助化療療效評價中的價值[J];中華超聲影像學(xué)雜志;2016年03期

2 李燁;劉愛連;曹會志;田士峰;劉靜紅;汪禾青;張婷;劉義軍;浦仁旺;劉曉鋒;;低管電壓結(jié)合低對比劑濃度對胃腸道惡性腫瘤供血動脈CT圖像質(zhì)量的影響[J];中華醫(yī)學(xué)雜志;2015年11期

3 朱勇;何光武;傅燕飛;王斌;陸峻;陳尚凡;;多層螺旋CT灌注成像對胃癌病理分化程度評估的研究[J];實用放射學(xué)雜志;2015年01期

4 曹國全;許化致;潘克華;陳偉建;郭翔;;320排容積CT全腦灌注成像掃描協(xié)議優(yōu)化研究[J];中華放射醫(yī)學(xué)與防護雜志;2014年05期

5 蔡惠芳;陳光強;朱建兵;陳建新;楊偉;胡翼江;龔建平;沈鈞康;;胃癌MSCT灌注成像與腫瘤血管生成關(guān)系的初步研究[J];實用放射學(xué)雜志;2014年05期

6 杜飛舟;顧明;關(guān)靜;李建浩;蔣銳;;320排容積CT上腹部一站式檢查初步探討[J];臨床放射學(xué)雜志;2011年08期

7 劉靜紅;劉偉;李智勇;;多層螺旋CT成像對胃癌的術(shù)前評估[J];中國CT和MRI雜志;2010年04期

8 李智勇;葛瑩;劉靜紅;王克禮;伍建林;;胃腫瘤CT灌注成像臨床價值的初步探討[J];大連醫(yī)科大學(xué)學(xué)報;2008年04期

9 張龍江;姜濱;沈文;祁吉;;胃CT灌注成像的初步研究[J];放射學(xué)實踐;2007年08期

10 邵燕惠;錢農(nóng);薛躍君;戴伊紅;;多層螺旋CT灌注成像對慢性阻塞性肺疾病的診斷價值[J];中華放射學(xué)雜志;2008年03期

相關(guān)碩士學(xué)位論文 前1條

1 孫宗瓊;64層螺旋CT灌注成像在胃癌的臨床應(yīng)用研究[D];蘇州大學(xué);2015年

【共引文獻】

相關(guān)期刊論文 前10條

1 林秉淞;;超聲內(nèi)鏡與多層螺旋CT在胃癌術(shù)前分期中應(yīng)用研究[J];中國CT和MRI雜志;2017年08期

2 殷小平;左紫薇;徐英進;王佳寧;劉懷軍;梁廣路;;能譜CT單能量成像聯(lián)合自適應(yīng)迭代算法重組技術(shù)在腸系膜上動靜脈圖像質(zhì)量的臨床研究[J];臨床放射學(xué)雜志;2017年06期

3 劉曉冬;劉愛連;劉靜紅;劉義軍;孫美玉;李燁;趙瑩;方鑫;袁剛;;Revolution CT全胃灌注掃描時間間隔對正常胃壁灌注數(shù)據(jù)的影響[J];中國臨床醫(yī)學(xué)影像雜志;2017年06期

4 丁晨e，

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