【摘要】：目的:分析過(guò)度運(yùn)動(dòng)狀態(tài)下SD大鼠心血管內(nèi)分泌癥狀特征。方法:選擇雄性SD大鼠40只,依據(jù)體重隨機(jī)劃分成安靜對(duì)照組、中等過(guò)度運(yùn)動(dòng)組、強(qiáng)過(guò)度運(yùn)動(dòng)組以及力竭運(yùn)動(dòng)組,對(duì)于運(yùn)動(dòng)組的大鼠,需每天在跑臺(tái)上完成不同程度的8周過(guò)度運(yùn)動(dòng)訓(xùn)練,采用仿射免疫法測(cè)定大鼠心機(jī)細(xì)胞中內(nèi)皮素ET、血管緊張素AGTⅡ、心機(jī)細(xì)胞膜上受體ETR等內(nèi)分泌癥狀特征的變化情況。結(jié)果:強(qiáng)過(guò)度運(yùn)動(dòng)組大鼠的AGTⅡ含量均顯著低于安靜組(P0.01),力竭運(yùn)動(dòng)組大鼠的AGTⅡ含量與安靜組無(wú)顯著性差異;強(qiáng)過(guò)度運(yùn)動(dòng)組大鼠的ET含量均顯著低于安靜組大鼠(P0.01);力竭運(yùn)動(dòng)組大鼠和中等過(guò)度運(yùn)動(dòng)組的ET含量和安靜組相比并無(wú)顯著性差異;強(qiáng)過(guò)度運(yùn)動(dòng)組大鼠的ETR值顯著增加(P0.05),力竭運(yùn)動(dòng)組大鼠的ETR值顯著降低(P0.01);各運(yùn)動(dòng)組大鼠的ANP含量和安靜組相比均顯著增高(P0.05、P0.01),力竭運(yùn)動(dòng)組大鼠的ANP含量比安靜組顯著降低(P0.05)。結(jié)論:中等過(guò)度運(yùn)動(dòng)可明顯改善內(nèi)分泌功能,而過(guò)度運(yùn)動(dòng)阻礙內(nèi)分泌系統(tǒng)的功能。
[Abstract]:Objective: to analyze the characteristics of cardiovascular endocrine symptoms in SD rats. Methods: forty male SD rats were randomly divided into three groups according to their body weight: quiet control group, moderate overexercise group, strong overexercise group and exhausted exercise group. After 8 weeks of overtraining, the changes of endocrine symptoms such as endothelin (ET,) angiotensin 鈪，

本文編號(hào)：2419434