【摘要】：正腫瘤抑制蛋白p16免疫組化染色是評價人乳頭狀瘤病毒(HPV)感染狀態(tài)的主要依據(jù),同時p16陽性也是提示HPV相關(guān)性口咽鱗狀細(xì)胞癌預(yù)后良好的標(biāo)志物。目前p16陽性重要的評價指標(biāo)包括p16陽性細(xì)胞數(shù)及陽性融合細(xì)胞數(shù),通常將75%陽性細(xì)胞定義為p16陽性,而≤25%陽性細(xì)胞定義為p16陰性,另外將50%陽性細(xì)胞且伴25%融
[Abstract]:Immunohistochemical staining of positive tumor suppressor protein p16 is the main basis for evaluating the status of (HPV) infection of human papillomavirus (HPV), and the positive expression of p16 is also a good prognostic marker for HPV associated oropharyngeal squamous cell carcinoma (OSCC). At present, the number of p16 positive cells and the number of positive fusion cells are the most important indexes for p16 positive, which usually define 75% of positive cells as p16 positive, 鈮，

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