【摘要】：目的分析急進(jìn)性后部型早產(chǎn)兒視網(wǎng)膜病(AP-ROP)的危險因素。方法采用回顧性病例對照研究方法 ,納入2012年3月至2014年9月在廣東省婦幼保健院住院的55例AP-ROP先證者和110例普通ROP患兒,兩者按1∶2進(jìn)行配比,匹配條件:普通ROP患兒、入院時間最接近,收集、整理資料。結(jié)果胎齡32周(χ~2=8.584),出生體質(zhì)量1 250 g(χ~2=3.960),吸氧(χ~2=7.015),吸氧≥14 d(χ~2=22.273),機(jī)械通氣(χ~2=10.104),機(jī)械通氣≥14 d(χ~2=12.579),使用PS(χ~2=10.942),新生兒貧血(χ~2=8.462),輸血≥2次(χ~2=41.734),RDS(χ~2=11.733),新生兒肺炎(χ~2=25.536),呼吸暫停(χ~2=23.468),BPD(χ~2=8.319),顱內(nèi)出血(χ~2=6.478),代謝性酸中毒(χ~2=8.317),視網(wǎng)膜出血(χ~2=10.188)與AP-ROP顯著相關(guān)(P0.05)。在單因素分析基礎(chǔ)上運用條件Logistic回歸分析,輸血≥2次(OR:14.956)和呼吸暫停(OR:7.590)是AP-ROP的獨立危險因素。結(jié)論 AP-ROP的發(fā)生與出生胎齡小、出生體重低、氧療及相關(guān)并發(fā)癥(如呼吸窘迫綜合征、視網(wǎng)膜出血等)有關(guān),輸血和呼吸暫停是AP-ROP的獨立危險因素。
[Abstract]:Objective to analyze the risk factors of retinopathy (AP-ROP) of advanced posterior preterm infants. Methods A retrospective case-control study was conducted in 55 AP-ROP proband and 110 ordinary ROP patients hospitalized in Guangdong Maternal and Child Health Care Hospital from March 2012 to September 2014. The two groups were matched at 1:2. Matching conditions: common ROP children, admission time is the closest, collection, collation of data. Results the gestational age was 32 weeks (蠂 ~ 2 + 8.584), birth weight was 1 250g (蠂 ~ 2) 3.960, oxygen intake was (蠂 ~ 2) 7.015, oxygen intake was more than 14 days (蠂 ~ (2) ~ 2 ~ (22. 273), mechanical ventilation (蠂 ~ 2 ~ 2 ~ 10. 104), mechanical ventilation 鈮，

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