【摘要】：目的運用生物電阻抗分析(Bioelectric Impedance Analysis,BIA)評價慢性腎臟病(Chronic Kidney Disease,CKD)患者的營養(yǎng)狀況,并將其和生化指標(biāo)評估結(jié)果對比,為早期發(fā)現(xiàn)CKD患者營養(yǎng)不良狀態(tài)、及時給予營養(yǎng)干預(yù)提供有效參考。方法隨機選擇2014年11月-12月期間在某三甲醫(yī)院CKD管理中心注冊的CKD患者57例,根據(jù)其浮腫指數(shù)、依從性等共納入研究對象44例,應(yīng)用BIA法評估研究對象的營養(yǎng)狀況并與生化指標(biāo)評價結(jié)果比較。結(jié)果BIA和生化檢查營養(yǎng)不良率(含營養(yǎng)不良風(fēng)險)分別為45.4%和25%,且差異有統(tǒng)計學(xué)意義(χ~2=4.034,P0.05)。女性身體細(xì)胞量、細(xì)胞內(nèi)水分和蛋白質(zhì)的質(zhì)量均顯著高于男性(P0.05),而男、女性ALB水平差異無統(tǒng)計學(xué)意義。在ALB水平正常的CKD患者中,其體細(xì)胞量、細(xì)胞內(nèi)水分、蛋白質(zhì)、骨骼肌、體脂肪均低于正常范圍。BIA營養(yǎng)不良的研究對象的骨骼肌量和血清白蛋白(serum Albumin,ALB)水平顯著相關(guān)(r=0.58,P0.05)。結(jié)論 CKD患者營養(yǎng)不良率較高;與生化檢查相比,BIA可早期發(fā)現(xiàn)CKD患者的營養(yǎng)不良狀態(tài)和營養(yǎng)不良風(fēng)險,有利于醫(yī)生對營養(yǎng)不良患者及時采取有效的營養(yǎng)干預(yù)。
[Abstract]:Objective to evaluate the nutritional status of patients with chronic kidney disease (Chronic Kidney Disease,CKD) by bioelectric impedance analysis (Bioelectric Impedance Analysis,BIA) and compare the results with biochemical indexes to provide an effective reference for early detection of malnutrition in CKD patients and timely nutritional intervention. Methods A total of 57 CKD patients were randomly selected from November to December 2014 in CKD Management Center of a third Class A Hospital. According to their swelling index and compliance, 44 patients were included in the study. The nutritional status of the subjects was evaluated by BIA method and compared with the results of biochemical evaluation. Results the malnutrition rates of BIA and biochemical examination (including malnutrition risk) were 45.4% and 25%, respectively, and the difference was statistically significant (蠂 ~ 2 / 24.034). The quantity of body cells, the quality of water and protein were significantly higher in female than in male (P0.05), but there was no significant difference in ALB level between male and female. In CKD patients with normal ALB level, there was a significant correlation between the amount of somatic cells, intracellular water, protein, skeletal muscle, body fat and serum albumin (serum Albumin,ALB) levels in subjects with normal range of .BIA-dystrophy (P 0.05). Conclusion the malnutrition rate of CKD patients is higher than that of biochemical examination, and the malnutrition status and risk of CKD patients can be detected early, which is helpful for doctors to take effective nutritional intervention on malnutrition patients in time.
【作者單位】： 四川大學(xué)華西公共衛(wèi)生學(xué)院(華西第四醫(yī)院);四川大學(xué)華西醫(yī)院臨床營養(yǎng)科;
【基金】：慢性腎臟病終末期干體重評價標(biāo)準(zhǔn)的建立(2015SZ0144)
【分類號】：R692
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本文編號：2256972