發(fā)布時間：2018-06-05 00:52

  本文選題：胃息肉 + 幽門螺旋桿菌��； 參考：《石河子大學(xué)》2017年碩士論文

【摘要】：目的:了解胃鏡下胃息肉的病理特征及臨床特點,探討胃息肉的臨床特點及其與幽門螺桿菌(HP)感染的關(guān)系,為治療和診斷胃息肉提供幫助及臨床依據(jù)。方法:回顧分析2015年10月份到2016年10月份石河子大學(xué)醫(yī)學(xué)院第一附屬醫(yī)院消化內(nèi)鏡中心行胃鏡診斷胃息肉患者的臨床資料,分析患者年齡、性別,胃息肉的大小、位置及其與幽門螺桿菌感染之間的關(guān)系,從而進一步指導(dǎo)內(nèi)鏡下行微創(chuàng)治療或者外科手術(shù)治療。由有內(nèi)鏡操作資格的內(nèi)鏡醫(yī)師對患者的食管、胃底、胃體、胃角、胃竇、十二指腸進行各方面仔細檢查,在胃鏡檢查時如發(fā)現(xiàn)胃息肉則根據(jù)胃內(nèi)標志和黏膜特點確定發(fā)生的部位,每一病變至少取一塊組織進行組織病理學(xué)檢查,采用HE染色方法檢查幽門螺旋桿菌有無感染,詳細記錄胃息肉數(shù)量、形態(tài)、大小、部位等。結(jié)果:石河子大學(xué)醫(yī)學(xué)院第一附屬醫(yī)院2015年10月到2016年10月兵團消化內(nèi)鏡中心檢測出門診及住院胃息肉的患者共779例,其中男性患者248例,女性患者531例,男女比例為1:2.1,年齡在15-90歲,平均年齡55±11歲;本組資料中一共發(fā)現(xiàn)息肉976枚,單發(fā)息肉632例,多發(fā)息肉共147例;高發(fā)年齡段41-60歲(58.9%),年齡在15-90歲,58.9%的胃息肉患者年齡在41-60歲之間,單發(fā)息肉632例(81.2%),多發(fā)息肉147例(18.8%);大多數(shù)胃息肉的直徑1.0cm,共為694例(89.1%);胃息肉中幽門螺桿菌的感染率為37.7%;不同部位的胃息肉存在大小的差異(P0.05),不同病理類型的胃息肉之間的HP感染也存在差異(P0.05),胃底胃體部息肉HP的感染率高于其他部位(P0.05)。結(jié)論:不同部位的胃息肉存在大小的差異,大多胃息肉直徑比較小,小于1.0cm,主要位于胃底和胃體;增生性息肉的HP感染率均高于炎性息肉和腺瘤性息肉,增生性息肉的發(fā)生可能與HP感染相關(guān);幽門螺旋桿菌感染對于發(fā)生在胃底胃體的增生性息肉、炎性息肉較其他部位的上述病理型息肉更密切。
[Abstract]:Objective: to investigate the pathological and clinical features of gastric polyps under gastroscopy, and to explore the relationship between the clinical features of gastric polyps and the infection of Helicobacter pylori (HP) in order to provide help and clinical basis for the treatment and diagnosis of gastric polyps. Methods: the clinical data of patients with gastric polyps diagnosed by endoscopy in the first affiliated Hospital of Shihezi University Medical College from October 2015 to October 2016 were analyzed retrospectively. The age, sex and size of gastric polyps were analyzed. Location and its relationship with Helicobacter pylori infection further guide endoscopic minimally invasive or surgical treatment. The patients' esophagus, fundus, body, horn, antrum and duodenum were carefully examined by a qualified endoscopic physician. If a gastric polyp was found at the time of gastroscopy, the location of gastric polyp was determined according to the characteristics of the stomach and mucosa. At least one piece of tissue was taken for histopathological examination, and HE staining was used to detect the infection of Helicobacter pylori. Record the number, shape, size and location of gastric polyps in detail. Results: from October 2015 to October 2016, 779 patients with gastric polyps were detected in the first affiliated Hospital of Shihezi University Medical College, including 248 male patients and 531 female patients. The ratio of male and female was 1: 2.1, aged 15-90 years, with an average age of 55 鹵11 years. A total of 976 polyps, 632 single polyps and 147 multiple polyps were found in this group, and 41-60 years old, 58.9% of the patients with gastric polyps aged 15-90 years were between 41-60 years old. 632 cases of single polyp and 147 cases of multiple polyps were compared to 18.8%; the diameter of most gastric polyps was 1.0 cm, 694 cases were 89. 1%; the infection rate of Helicobacter pylori in gastric polyps was 37. 7%; there were differences in the size of gastric polyps in different parts (P 0. 05), and in different pathological types of gastric polyps. The infection rate of HP in gastric fundus gastric body polyp was higher than that in other parts. Conclusion: there are differences in the size of gastric polyps in different parts, the diameter of most gastric polyps is smaller than 1.0 cm, mainly located in the stomach fundus and gastric body, the HP infection rate of proliferative polyps is higher than that of inflammatory polyps and adenomatous polyps. The occurrence of proliferative polyps may be related to HP infection, and Helicobacter pylori infection is more closely related to the pathological polyps of the gastric fundus than that of the inflammatory polyps in the gastric fundus.
【學(xué)位授予單位】：石河子大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R573

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本文編號：1979662