發(fā)布時間：2019-06-11 14:59

【摘要】：目的探討以關(guān)節(jié)炎就診的先天性無丙種球蛋白血癥臨床特點。方法收集2003年8月至2013年8月在南京醫(yī)科大學(xué)附屬兒童醫(yī)院以關(guān)節(jié)炎就診最后診斷為先天性無丙種球蛋白血癥的11例患兒資料,分析其臨床特點。結(jié)果 11例患兒多在關(guān)節(jié)腫痛后就診于骨科,診斷為感染及滑膜炎,部分行手術(shù)治療,關(guān)節(jié)炎癥累及膝、踝、肘和髖等大關(guān)節(jié),血清丙種球蛋白均明顯低下。診斷明確后,予靜脈滴注丙種球蛋白(IVIG)及非甾體類抗炎藥物(NSAIDs),病情得到控制,關(guān)節(jié)未發(fā)生進(jìn)一步損害。結(jié)論關(guān)節(jié)炎患兒應(yīng)常規(guī)行免疫功能檢查,早期診斷和合理治療是改善預(yù)后的關(guān)鍵。
[Abstract]:Objective to investigate the clinical characteristics of congenital non-gamma globulin in patients with arthritis. Methods from August 2003 to August 2013, the data of 11 children with congenital non-gamma globulin diagnosed as congenital gamma globulin in the affiliated Children's Hospital of Nanjing Medical University were collected and their clinical features were analyzed. Results most of the 11 children were diagnosed as infection and synovitis after joint swelling and pain. Some of them were treated surgically. Arthritis involved knee, ankle, elbow and hip, and serum gamma globulin was significantly lower. After diagnosis, intravenous infusion of gamma globulin (IVIG) and non-steroidal anti-inflammatory drug (NSAIDs), were controlled, and no further joint damage occurred. Conclusion routine immune function examination should be performed in children with arthritis. Early diagnosis and reasonable treatment are the key to improve prognosis.
【作者單位】： 南京醫(yī)科大學(xué)附屬兒童醫(yī)院風(fēng)濕免疫科;
【分類號】：R725.9
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本文編號：2497279