發(fā)布時(shí)間：2019-07-10 14:29

【摘要】：目的藥物治療帕金森病(PD)便秘會(huì)導(dǎo)致依賴性,甚至造成胃腸道其他損害。文中通過觀察撳針俞募配穴法和口服枸櫞酸枸櫞酸莫沙必利片2種治療方法,比較患者在接受治療后的肛腸動(dòng)力學(xué)和PD便秘癥狀的改善程度。方法回顧性分析2013年5月至2016年9月期間浙江省人民醫(yī)院針灸科和北京東方醫(yī)院腦病科門診收治的PD便秘患者60例,隨機(jī)分為對(duì)照組(n=30)和試驗(yàn)組(n=30)。對(duì)照組采用口服枸櫞酸莫沙必利片,治療組采用撳針治療。通過自身對(duì)照和組間對(duì)照比較兩組臨床療效、便秘患者生活質(zhì)量(PAC-QOL)量表評(píng)分和肛門直腸動(dòng)力學(xué)檢查結(jié)果。結(jié)果治療組總有效率81.7%,顯著高于對(duì)照組(70%),組間比較差異有統(tǒng)計(jì)學(xué)意義(P0.05);治療組和對(duì)照組均可改善PAC-QOL量表評(píng)分情況,與治療前比較差異均有統(tǒng)計(jì)學(xué)意義(P0.01),治療后組間比較差異無統(tǒng)計(jì)學(xué)意義(P0.05);兩組與治療前比較,肛腸動(dòng)力學(xué)指標(biāo)差異有統(tǒng)計(jì)學(xué)意義(P0.05),組間比較差異無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論撳針和枸櫞酸莫沙必利片治療PD便秘癥狀均可改善患者的生活質(zhì)量和肛腸動(dòng)力學(xué),療效近似。但撳針俞募配穴法在改善PD便秘癥狀中總有效率高于枸櫞酸莫沙必利片,且操作方便、患者痛苦小,值得臨床推廣應(yīng)用。
[Abstract]:Objective Drug treatment of (PD) constipation in Parkinson's disease will lead to dependence and even other gastrointestinal damage. In this paper, the anorectal motility and the improvement of PD constipation symptoms were compared by observing the acupoint method and oral mosapride citrate tablets. Methods from May 2013 to September 2016, 60 patients with PD constipation treated in the Department of Acupuncture and moxibustion, Zhejiang people's Hospital and the Department of Encephalology, Beijing Oriental Hospital were randomly divided into control group (n 鈮，

本文編號(hào)：2512659