發(fā)布時間：2019-01-21 13:19

【摘要】：目的通過臨床觀察，論證枳術(shù)寬中膠囊聯(lián)合凝結(jié)芽孢桿菌治療功能性便秘的實用性、科學性，并證明該種聯(lián)合治療是治療便秘的有效方法。 方法收集2012年5月份到2013年5月份，就診于山西省人民醫(yī)院消化科門診并符合功能性便秘診斷標準的病人共60例，，隨機分為對照組1、對照組2、治療組，每組各20例。對照組1給予枳術(shù)寬中膠囊口服，對照組2給予凝結(jié)芽孢桿菌活菌片口服，治療組給予枳術(shù)寬中膠囊和凝結(jié)芽孢桿菌活菌片口服。在治療前及治療一個月后，分別對3組患者的中醫(yī)臨床癥狀積分進行統(tǒng)計，觀察分析三組的療效。 結(jié)果三組患者治療結(jié)束后，枳術(shù)寬中膠囊組（對照組1）治愈1例（5%），顯效6例（30%），有效8例（40%），無效5例（25%），總顯效率35%，總有效率75%；凝結(jié)芽孢桿菌組（對照組2）治愈2例（10%），顯效6例（30%），有效9例（45%），無效3例（15%），總顯效率40%，總有效率85%；枳術(shù)寬中膠囊聯(lián)合凝結(jié)芽孢桿菌組（治療組）治愈5例（25%），顯效10例（50%），有效4例（20%），無效1例（5%），總顯效率75%，總有效率95%。經(jīng)統(tǒng)計學分析，三組治療結(jié)果在總有效率方面差異無統(tǒng)計學意義（P0.05），但在顯效率方面差異有統(tǒng)計學意義（P0.05），說明治療組療效優(yōu)于對照組1、2；治療結(jié)束后對三組患者中醫(yī)癥狀積分進行比較，差異具有統(tǒng)計學意義（P0.05），說明枳術(shù)寬中膠囊聯(lián)合凝結(jié)芽孢桿菌對功能性便秘的癥狀改善情況優(yōu)于兩種藥物的單獨治療情況。 結(jié)論枳術(shù)寬中膠囊聯(lián)合凝結(jié)芽孢桿菌治療功能性便秘優(yōu)于傳統(tǒng)的口服藥治療，值得臨床推廣。
[Abstract]:Objective to demonstrate the practicability and scientificity of Zhizhukanzhong capsule combined with Bacillus coagulans in the treatment of functional constipation, and to prove that the combined therapy is an effective method for the treatment of constipation. Methods from May 2012 to May 2013, 60 patients who met the diagnostic criteria of functional constipation were randomly divided into control group (n = 20), control group (n = 2) and treatment group (n = 20). Control group 1 was administered with Zhizhukanzhong capsule, control group 2 with Bacillus coagulans active bacteria tablets, treatment group with trifoliate orange Kuanzhuanzhong capsule and Bacillus coagulans active bacteria tablet. Before and one month after treatment, the clinical symptom scores of three groups of patients were statistically analyzed and the curative effects of the three groups were observed and analyzed. Results after treatment, 1 case (5%) was cured, 6 cases (30%) were significantly effective, 8 cases (40%) were effective, 5 cases (25%) were ineffective, the total effective rate was 35% and the total effective rate was 75% in the Zhizhoukanzhong capsule group (control group 1). In the control group, 2 cases (10%) were cured, 6 cases (30%) were cured, 9 cases (45%) were effective, 3 cases (15%) were ineffective, the total effective rate was 40% and the total effective rate was 85%. In the treatment group, 5 cases (25%) were cured, 10 cases (50%) were effective, 4 cases (20%) were effective, 1 case (5%) was ineffective, the total effective rate was 7575% and the total effective rate was 95%. By statistical analysis, the results of the three groups in the total effective rate difference was not statistically significant (P0.05), but there was significant difference in the effective rate (P0.05), indicating that the therapeutic effect of the treatment group is better than that of the control group (1 / 2); After the treatment, the scores of TCM symptoms in the three groups were compared and the difference was statistically significant (P0.05). The results showed that the symptom improvement of Zhizhushuanzhong capsule combined with Bacillus coagulans on functional constipation was better than that of two drugs alone. Conclusion Zhizhushuanzhong capsule combined with Bacillus coagulans in the treatment of functional constipation is better than the traditional oral drug therapy, and it is worth popularizing.
【學位授予單位】：山西中醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2014
【分類號】：R574.62

【參考文獻】

相關(guān)期刊論文 前10條

1 祁守鑫;田玉美治療氣虛便秘的經(jīng)驗[J];安徽中醫(yī)臨床雜志;1998年02期

2 錢耀明;李永健;樂楓;張嘯剛;沈國平;;行舟湯治療虛證功能性便秘60例[J];安徽中醫(yī)學院學報;2010年05期

3 楊國晶,王麗娟,趙莉;電針并中藥治療老年習慣性便秘36例[J];白求恩醫(yī)科大學學報;2001年06期

4 王愛明;黃忠誠;唐佳新;呂建華;毛先華;;盆底肌功能失調(diào)型便秘的生物反饋治療及護理[J];結(jié)直腸肛門外科;2007年02期

5 洪雪峰;;林禾禧主任醫(yī)師治療便秘臨床經(jīng)驗[J];福建中醫(yī)藥;2007年04期

6 張小軍;便秘從痰論治體會[J];甘肅中醫(yī);2002年06期

7 王慧芬;趙洪川;;功能性便秘與心理因素及自主神經(jīng)功能相關(guān)性的研究進展[J];國際消化病雜志;2007年03期

8 張秀;李承惠;賈山;王連杰;趙團結(jié);;280例慢性功能性便秘患者生物反饋治療的臨床研究[J];北京醫(yī)學;2013年08期

9 郭慧君;王知佳;;中醫(yī)辨證分型治療老年功能性便秘80例[J];河北中醫(yī);2009年05期

10 許江勇;;生物反饋治療功能性便秘30例[J];護理實踐與研究;2007年07期

本文編號：2412701