發(fā)布時間：2018-12-30 10:41

【摘要】：目的:本研究擬探討引起急性膽系疾病患者肌鈣蛋白升高的臨床相關(guān)因素,進(jìn)一步提高對急性膽系疾病患者肌鈣蛋白升高的臨床認(rèn)識。方法:連續(xù)收集115例臨床上確診的急性膽系疾病患者,根據(jù)肌鈣蛋白檢測結(jié)果分為肌鈣蛋白升高組18例,肌鈣蛋白正常組97例,記錄納入樣本的臨床資料,包括性別、年齡、既往有無冠心病及其等危癥、急性膽系疾病病情嚴(yán)重程度、膽囊擴(kuò)張或膽管擴(kuò)張等,采用Logistic回歸分析急性膽系疾病患者合并肌鈣蛋白升高的相關(guān)危險因素。結(jié)果:在115例確診急性膽系疾病的患者中,18例患者肌鈣蛋白升高,發(fā)生率為15.65%,通過單因素分析發(fā)現(xiàn)急性膽系疾病病情嚴(yán)重程度,C反應(yīng)蛋白(CRP)、谷丙轉(zhuǎn)氨酶(ALT)、谷草轉(zhuǎn)氨酶(AST)、總膽紅素(TBIL)、膽管擴(kuò)張與急性膽系疾病肌鈣蛋白升高差異有統(tǒng)計學(xué)意義(P0.05),通過多因素Logistic回歸分析顯示C反應(yīng)蛋白(OR=1.052;90%CI,1.024~1.082),ALT(OR=1.006;90%CI,1.002~1.011),疾病嚴(yán)重程度(OR=4.681;90%CI,1.132~19.361)是急性膽系疾病患者肌鈣蛋白升高的獨立危險因素。α入=0.05,α出=0.10,P0.1有統(tǒng)計學(xué)意義。結(jié)論:C反應(yīng)蛋白(CRP)、谷丙轉(zhuǎn)氨酶(ALT)、疾病病情嚴(yán)重程度是急性膽系疾病患者肌鈣蛋白升高的獨立危險因素。
[Abstract]:Objective: to investigate the clinical factors related to the elevation of cardiac troponin in patients with acute biliary diseases and to improve the clinical understanding of the elevation of troponin in patients with acute biliary diseases. Methods: 115 patients with acute biliary diseases were collected and divided into 18 patients with elevated troponin and 97 patients with normal cardiac troponin according to the results of cardiac troponin test. The clinical data including sex and age were recorded. Logistic regression analysis was used to analyze the risk factors associated with elevated cardiac troponin in patients with acute biliary diseases such as coronary heart disease (CHD) and its isotherapies, severity of acute biliary diseases, gallbladder dilatation or bile duct dilatation. Results: of the 115 patients with acute biliary diseases, 18 had elevated troponin (15.65%). The severity of acute biliary diseases and C-reactive protein (CRP),) were found by univariate analysis. Glutamic pyruvic transaminase (ALT),) and total bilirubin (TBIL), (AST),) were significantly higher than those in acute biliary diseases (P0.05). Identification of C-reactive protein (OR=1.052;) by multivariate Logistic regression analysis 90CIN 1.024 1.082), ALT (OR=1.006;90%CI,1.002~1.011), severity of disease (OR=4.681;) 90CII 1.132 ~ 19.361) is an independent risk factor for the elevation of cardiac troponin in patients with acute biliary diseases, 偽 -input = 0.05, 偽 -output = 0.10p _ (0.1). Conclusion: the severity of C-reactive protein (CRP), glutamate-alanine aminotransferase (ALT),) disease is an independent risk factor for the elevation of troponin in patients with acute biliary diseases.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R575.6

【參考文獻(xiàn)】

相關(guān)期刊論文 前7條

1 楊士賢;吳鐵鏞;劉曉剛;;膽心綜合征220例誤診文獻(xiàn)分析[J];解放軍醫(yī)藥雜志;2015年06期

2 張鎖龍;;高敏感性肌鈣蛋白T對急性非ST段抬高型心肌梗死早期診斷的臨床意義[J];中國現(xiàn)代醫(yī)生;2014年03期

3 周穎一;周麗娜;王強(qiáng);;膽心綜合征患者的心電圖分析[J];中國基層醫(yī)藥;2012年03期

4 秦玲,王立波,谷蘭梨樹縣中醫(yī)院內(nèi)科;膽心綜合征發(fā)生機(jī)制的研究進(jìn)展[J];臨床肝膽病雜志;2002年04期

5 范惠珠,郭國徽,眭大權(quán),陳俊;膽心綜合征215例臨床分析[J];現(xiàn)代診斷與治療;1997年02期

6 聶超群,張新高;膽心綜合征[J];醫(yī)學(xué)綜述;1996年07期

7 劉寶華;王志如;鐘進(jìn)華;徐有奇;袁立功;;膽道內(nèi)壓力與膽汁返流關(guān)系的實驗觀察[J];中華實驗外科雜志;1990年01期

，

本文編號：2395469