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基于幽門螺旋桿菌檢測上消化道大出血診療研究

發(fā)布時間:2018-12-15 11:23
【摘要】:目的:研究一種采用幽門螺旋桿菌檢測的方法實現(xiàn)對上消化道大出血的診療和根治。為臨床消化內(nèi)科疾病提供指導意義。方法:研究以100例感染幽門螺旋桿菌的上消化道大出血患者,對于幽門螺旋桿菌的酵母菌,從人體非黏膜組織中提取出活體檢測樣本,采用針吸標本,通過組織化學分析方法或細胞化學檢驗方法獲得幽門螺旋桿菌菌細胞或通過菌種培養(yǎng)方法,在無菌條件下取得,培養(yǎng)結(jié)果呈陽性。幽門螺桿菌可刺激胃部前葉的發(fā)育內(nèi)分泌激素,使其分泌TSH,使胃部分泌激素合成和分泌幽門螺桿菌素激素發(fā)育的釋放量快速增加。結(jié)果:采用SPSS12.0軟件進行統(tǒng)計學分析,采取配對t檢驗,得到幽門螺旋桿菌的活性相當于變形桿菌的400倍,基于概率分布特性,得到幽門螺旋桿菌的I型含有Cag A和Vac A基因并表達兩種蛋白,Ⅱ型不含Cag A基因,與胃疾病關系較為密切。結(jié)論:進行幽門螺旋桿菌陽性檢測,并配合克拉霉素和奧美拉唑及阿莫西林三聯(lián)用藥治療可以有效抑制上消化道大出血,具有較好的治療效果。
[Abstract]:Objective: to study a method of detection of Helicobacter pylori for diagnosis and treatment of upper gastrointestinal hemorrhage. To provide guidance for clinical digestive diseases. Methods: 100 patients with massive hemorrhage of upper digestive tract infected with Helicobacter pylori were studied. The cells of Helicobacter pylori were obtained by histochemical analysis or cytochemical examination. The culture results were positive under aseptic conditions. Helicobacter pylori can stimulate the development of endocrine hormones in the anterior lobe of the stomach and make the secretion of TSH, make the secretion hormone synthesis and release of Helicobacter pylori hormone production increase rapidly. Results: the results showed that the activity of Helicobacter pylori was 400 times of that of Proteus, based on the characteristics of probability distribution. Type I of Helicobacter pylori contained Cag A and Vac A genes and expressed two kinds of proteins. Type 鈪,

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