發(fā)布時間：2018-06-04 06:12

  本文選題：雙能CT + 肝臟門靜脈期��； 參考：《中國醫(yī)學(xué)計算機成像雜志》2017年02期

【摘要】：目的:探比較雙能CT(DECT)的單能量圖像和融合圖像在肝臟門靜脈期增強的應(yīng)用效果。方法:配置不同濃度碘對比劑溶液制成體模原型,在Siemens SOMATOM Definition Flash掃描儀上,采用上腹部推薦協(xié)議先后執(zhí)行常規(guī)120k Vp掃描和100/Sn 140k Vp雙能掃描。其中,后者所采集圖像數(shù)據(jù)分別重建得到權(quán)重配比為0.5的線性融合圖像(M_0.5)、最優(yōu)非線性融合圖像(OCM)和根據(jù)對比度噪聲比(CNR)能譜曲線優(yōu)選的單能量圖像(Mono)。計算對比度、CNR和品質(zhì)因數(shù)(FOM)以比較圖像質(zhì)量�；仡櫡治�30例上腹部雙能CT增強檢查,比較門靜脈期不同重建圖像的肝實質(zhì)和門靜脈主干的增強幅度,并采用6分量表法對最大密度投影(MIP)和容積再現(xiàn)(VR)圖像進行主觀評價。結(jié)果:體模實驗中,與120k Vp圖像相比,M_0.5圖像的對比度無顯著差異(P=0.239)但CNR提高16.3%;DECT三種重建圖像中,OCM和Mono圖像的對比度、CNR分別比M_0.5圖像提高33.3%、32.3%和16.6%、6.1%;DECT三種重建圖像的FOM比120k Vp圖像分別提高10.3%、94.2%和24.5%。臨床病例的門靜脈期OCM和Mono圖像的肝實質(zhì)和門靜脈主干增強幅度比M_0.5圖像分別提高20.4%、19.2%和16.2%、15.9%;MIP和VR圖像的評分中,OCM組和Mono組無顯著差別(P=0.317),均顯著高于M_0.5組(P0.001)。結(jié)論:在上腹部DECT增強檢查中,為提高肝臟門靜脈期圖像增強效果應(yīng)重建OCM圖像。
[Abstract]:Aim: to compare the application effect of single energy image and fusion image of dual energy CTD ECT in portal vein phase of liver. Methods: the phantom prototype was made with different concentrations of iodine contrast agent solution. The routine 120k VP scan and the 100/Sn 140k VP dual-energy scan were performed on the Siemens SOMATOM Definition Flash scanner using the epigastric recommendation protocol. Among them, the image data collected by the latter can reconstruct respectively the linear fusion image with weighted ratio of 0.5, the optimal nonlinear fusion image OCMM) and the single energy image selected according to the contrast noise ratio (CNR) energy spectrum curve. Contrast CNR and quality factor FOM were calculated to compare image quality. A retrospective analysis of 30 cases of epigastric dual-energy CT enhancement was performed to compare the enhancement of liver parenchyma and portal vein trunk in different reconstructed images of portal vein. The maximum density projection (MIP) and volumetric reconstruction (VRV) images were evaluated by 6 subscales. Results: in the phantom experiment, There was no significant difference in contrast between the two images (P < 0. 239), but CNR increased the contrast of Mono and OCM images in three reconstructed images by 33. 33% and 16. 6% higher than that of M0. 5 respectively. The FOM of the reconstructed images was 10. 3% and 24. 552% higher than that of 120 k VP images, respectively. The liver parenchyma and portal vein trunk enhancement amplitude of OCM and Mono images in portal phase of clinical cases were 20.442% and 16.20.90% higher than those of M0. 5, respectively. There was no significant difference between OCM group and Mono group, both of which were significantly higher than that of M + 0. 5 group (P 0.001). Conclusion: in the DECT enhancement of upper abdomen, OCM should be reconstructed in order to improve the enhancement effect of hepatic portal phase image.
【作者單位】： 第三軍醫(yī)大學(xué)西南醫(yī)院放射科;第三軍醫(yī)大學(xué)生物醫(yī)學(xué)工程學(xué)院;
【基金】：全軍醫(yī)學(xué)科技“十二五”重點課題(BWS11J015)
【分類號】：R575;R816.5
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本文編號：1976306