發(fā)布時間：2018-03-03 04:25

  本文選題：磁共振彈性成像　切入點：擴散加權(quán)成像　出處：《實用醫(yī)學雜志》2017年17期 　論文類型：期刊論文

【摘要】：目的對比磁共振彈力成像(MRE)與擴散加權(quán)成像(DWI)診斷慢性乙型病毒性肝炎(CBH)纖維化程度分級的價值。方法回顧性收集CBH患者93例,均行肝穿刺活檢,按照纖維化程度分級為S0-S4級;同期收集肝功能正常的健康查體者16例作為對照組。采用Spearman分析肝纖維化程度分級與彈性值、ADC值的相關(guān)性,采用ROC曲線分析肝彈性值、ADC值診斷纖維化程度分級的效能。結(jié)果患者組彈性值與纖維化程度分級呈顯著正相關(guān)(r=0.962,P0.01),患者組ADC值與纖維化程度分級呈顯著負相關(guān)(r=-0.823,P0.01);MRE/ADC檢測肝臟≥S1、≥S2、≥S3、S4級的ROC曲線下面積(AUC)分別為0.963/0.868、0.995/0.947、0.998/0.948、0.996/0.889,它們之間差異均具有統(tǒng)計學意義(均P0.05)。結(jié)論 MRE和DWI診斷肝纖維化程度分級均有較高的價值,MRE診斷效能優(yōu)于DWI。
[Abstract]:Objective to compare the value of magnetic resonance elastography (MRE) and diffusion-weighted imaging (DWI) in the diagnosis of fibrosis grade of chronic viral hepatitis B. methods 93 cases of CBH were collected retrospectively and all of them underwent liver biopsy and were classified as S0-S4 according to the degree of fibrosis. Sixteen healthy persons with normal liver function were collected as control group. The correlation between the degree of hepatic fibrosis and elastic value was analyzed by Spearman. The ROC curve was used to analyze the effectiveness of ROC value in the diagnosis of fibrosis grade. Results there was a significant positive correlation between the value of elasticity and the grade of fibrosis degree. The ADC value of patient group was negatively correlated with the grade of fibrosis degree. The area under the ROC curve of liver 鈮，

本文編號：1559529