發(fā)布時(shí)間：2019-07-16 07:25

【摘要】：目的:探討氨溴索治療小兒呼吸系統(tǒng)疾病的最佳給藥途徑。方法:選擇2014年6月-2016年6月我院兒科收治的呼吸系統(tǒng)疾病患兒120例,按就診單雙號(hào)順序分為靜脈滴注組和霧化吸入組,各60例。在常規(guī)治療基礎(chǔ)上,靜脈滴注組患兒給予鹽酸氨溴索注射液7.5 mg溶入50 m L 5%葡萄糖注射液中,ivgtt,bid;霧化吸入組患兒霧化吸入鹽酸氨溴索注射液7.5 mg,每次吸入15min,bid。兩組患兒均治療7 d。比較兩組患兒的臨床療效,氧分壓[p(O_2)]、二氧化碳分壓[p(CO_2)]、吸痰次數(shù)、臨床指標(biāo)和不良反應(yīng)發(fā)生情況。結(jié)果:霧化吸入組患兒的總有效率(96.67%)顯著高于靜脈滴注組(78.33%),p(O_2)水平顯著高于靜脈滴注組,吸痰次數(shù)顯著少于靜脈滴注組,發(fā)熱消失時(shí)間、氣喘消失時(shí)間、氧療時(shí)間、肺部Up音消失時(shí)間、咳嗽消失時(shí)間和平均住院時(shí)間均顯著短于靜脈滴注組,差異均有統(tǒng)計(jì)學(xué)意義(P0.05)。兩組患兒的p(CO_2)水平和不良反應(yīng)發(fā)生率比較,差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:氨溴索能有效治療小兒呼吸系統(tǒng)疾病,且霧化吸入的臨床療效優(yōu)于靜脈滴注。
[Abstract]:Objective: to explore the best administration of ambroxol in the treatment of respiratory diseases in children. Methods: from June 2014 to June 2016, 120 children with respiratory diseases were divided into intravenous drip group (n = 60) and atomization inhalation group (n = 60). On the basis of routine treatment, the children in the intravenous drip group were given ambroxol hydrochloric acid injection 7.5 mg and dissolved into 50 mL 5% glucose injection. The children in the ivgtt,bid; atomization inhalation group inhaled ambroxol hydrochloric acid injection 7.5 mg, each time for 15 min. The children in both groups were treated for 7 days. The clinical efficacy, partial pressure of oxygen [p (O 鈮，

本文編號(hào)：2514927