【摘要】：目的研究不同類(lèi)型幽門(mén)螺桿菌(HP)感染與兒童過(guò)敏性紫癜(HSP)之間的相關(guān)性,進(jìn)一步探討HSP的病因及發(fā)病機(jī)制。方法收集2014年9月至2015年12月青島大學(xué)附屬醫(yī)院兒科住院治療的100例HSP患兒作為病例組,同時(shí)選取50名門(mén)診健康查體同齡兒童作為對(duì)照組。進(jìn)行HP抗體檢測(cè)及分型檢測(cè)。結(jié)果 HSP組患兒的HP感染率明顯高于對(duì)照組(χ~2=4.170,P0.05)。其中有消化系癥狀HSP組HP感染率明顯高于無(wú)消化系癥狀組(χ~2=12.542,P0.05);HP陽(yáng)性HSP組Ⅰ型和中間型菌株總感染率明顯高于HP陽(yáng)性正常對(duì)照組(χ~2=8.499,P0.05);HP陽(yáng)性有消化系癥狀HSP組Ⅰ型菌株感染率明顯高于HP陽(yáng)性無(wú)消化系癥狀組(χ~2=8.433,P0.05),Ⅱ型菌株感染率明顯低于無(wú)消化系癥狀組(χ~2=12.046,P0.05)。結(jié)論兒童HSP的發(fā)病可能與HP感染有關(guān)。HSP兒童感染HP菌株類(lèi)型以Ⅰ型、中間型為主,且與臨床消化系統(tǒng)癥狀密切相關(guān)。
[Abstract]:Objective to study the relationship between different types of HP (HP) infection and (HSP) in children with Henoch-Schonlein purpura (HSP), and to explore the etiology and pathogenesis of HSP. Methods from September 2014 to December 2015, 100 children with HSP in the affiliated Hospital of Qingdao University were collected as the case group, and 50 children of the same age were selected as the control group. HP antibody detection and typing detection were carried out. Results the infection rate of HP in HSP group was significantly higher than that in control group (蠂 ~ 2 鈮，

本文編號(hào)：2481558