發(fā)布時(shí)間：2018-05-09 22:24

  本文選題：骨質(zhì)疏松 + 腹主動(dòng)脈鈣化　； 參考：《中國骨質(zhì)疏松雜志》2017年12期

【摘要】：目的研究中老年人腹主動(dòng)脈鈣化(AAC)與腰椎定量CT(QCT)骨密度(BMD)的相關(guān)性。方法納入2013年至2016年間招募的593名40~80歲(男性230人,女性363人)的健康志愿者測量受檢者身高、體質(zhì)量、腰圍,計(jì)算體重指數(shù)(BMI);進(jìn)行腰椎QCT骨密度測量,將原始圖像傳至圖像后處理工作站,采用Mindways QCT pro軟件,分別測量L1-3椎體骨密度。應(yīng)用Image J軟件測量腹主動(dòng)脈鈣化面積比。結(jié)果男、女性AAC患病率分別約為45.65%、28.37%;與無AAC組比較,男性、女性AAC組年齡更大,并且與腰椎BMD的差異均有統(tǒng)計(jì)學(xué)意義(P均0.05);男女腰椎BMD均與年齡呈負(fù)相關(guān)(r=-0.49、r=-0.73,P0.05),與BMI均無明顯相關(guān)性(r=0.02、r=0.01,P0.05);男、女性AAC均與年齡呈正相關(guān)(r=0.39、r=0.42,P0.05),與BMI均無明顯相關(guān)性(r=-0.03、r=-0.03,P0.05);男性BMD與AAC無明顯相關(guān)性(P=0.15),女性BMD與AAC呈低度負(fù)相關(guān)(r=-0.32,P0.05),校正年齡以后,女性BMD與AAC也無明顯相關(guān)性(P=0.08)。結(jié)論年齡為腹主動(dòng)脈鈣化和骨質(zhì)疏松發(fā)病的共同獨(dú)立的危險(xiǎn)因素,校正年齡后,男性、女性腰椎BMD與AAC均無顯著相關(guān)性。
[Abstract]:Objective to study the correlation between AAC and bone mineral density (BMDs) of lumbar quantitative CTQCTs in middle-aged and elderly patients. Methods A total of 593 healthy volunteers (230 males and 363 females) recruited from 2013 to 2016 were recruited to measure their height, body mass, waist circumference, body mass index (BMI) and bone mineral density (QCT) of lumbar vertebrae. Bone mineral density (BMD) of L1-3 vertebrae was measured by Mindways QCT pro software. The calcification area ratio of abdominal aorta was measured by Image J software. Results the prevalence rate of AAC in male and female was about 45.65 and 28.37.The male and female AAC group were older than those without AAC group. The difference between BMD and lumbar BMD was statistically significant (P < 0.05), and there was a negative correlation between lumbar BMD and age (P 0.05), but no significant correlation with BMI (P 0.05). There was no significant correlation between AAC and BMI in female, but there was no significant correlation between BMD and AAC in male, and there was a low negative correlation between BMD and AAC in female. There was no significant correlation between BMD and AAC after adjusted age. Conclusion Age is a common and independent risk factor for abdominal aortic calcification and osteoporosis. After adjusting for age, there is no significant correlation between BMD and AAC in male and female lumbar vertebrae.
【作者單位】： 貴州醫(yī)科大學(xué)第一附屬醫(yī)院放射科;北京積水潭醫(yī)院放射科;
【基金】：國家自然科學(xué)基金(81330043,81472139) 北京市科委項(xiàng)目(D131100005313013) 國家科技部十二五支撐計(jì)劃項(xiàng)目(2012BAI10B02)
【分類號(hào)】：R580;R816.8

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