發(fā)布時(shí)間：2018-01-09 18:23

  本文關(guān)鍵詞：宮頸癌患者磁共振體素不相干運(yùn)動(dòng)相關(guān)參數(shù)變化及意義　出處：《山東醫(yī)藥》2017年40期 　論文類(lèi)型：期刊論文

  更多相關(guān)文章： 宮頸癌 磁共振成像 擴(kuò)散加權(quán)成像 表觀擴(kuò)散系數(shù) 灌注相關(guān)體積分?jǐn)?shù)

【摘要】：目的探討宮頸癌患者3.0T磁共振體素不相干運(yùn)動(dòng)(IVIM)相關(guān)參數(shù)變化及其診斷價(jià)值。方法選擇宮頸癌患者29例作為觀察組,體檢健康女性24例作為對(duì)照組。兩組均進(jìn)行常規(guī)MRI及IVIM掃描,IVIM掃描采用13個(gè)b值,所得原始數(shù)據(jù)采用雙指數(shù)模型進(jìn)行分析,記錄并比較兩組標(biāo)準(zhǔn)表觀擴(kuò)散系數(shù)(標(biāo)準(zhǔn)ADC)、慢ADC、快ADC及灌注相關(guān)體積分?jǐn)?shù)(f),采用受試者工作特征曲線(ROC曲線)評(píng)價(jià)各參數(shù)對(duì)宮頸癌的診斷效能。結(jié)果觀察組與對(duì)照組標(biāo)準(zhǔn)ADC分別為(0.90±0.15)×10~(-3)、(1.15±0.23)×10~(-3)mm~2/s,慢ADC分別為(0.70±0.12)×10~(-3)、(0.97±0.21)×10~(-3)mm~2/s,快ADC分別為(6.66±2.02)×10~(-3)、(5.30±1.64)×10~(-3)mm~2/s,f分別為0.29±0.09、0.45±0.11;觀察組標(biāo)準(zhǔn)ADC、慢ADC、f均低于對(duì)照組(P均0.05),兩組快ADC比較差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。標(biāo)準(zhǔn)ADC、慢ADC、快ADC及f診斷宮頸癌的曲線下面積分別為0.79、0.86、0.32、0.84,以慢ADC最大,其臨界值為0.89×10~(-3)mm~2/s時(shí)診斷宮頸癌的敏感性為70%、特異性為90%。結(jié)論宮頸癌患者IVIM相關(guān)參數(shù)標(biāo)準(zhǔn)ADC、慢ADC及f均降低,上述參數(shù)檢測(cè)有助于宮頸癌的診斷。
[Abstract]:Objective to investigate the changes and diagnostic value of 3. 0T magnetic resonance voxel (VMI) related parameters in patients with cervical cancer. Methods 29 patients with cervical cancer were selected as the observation group. 24 healthy women were used as control group. Both groups underwent routine MRI and IVIM scanning using 13 b values. The original data were analyzed by double index model. Two groups of standard apparent diffusion coefficients (standard ADCA, slow ADCC, fast ADC and perfusion correlation volume fraction F) were recorded and compared. The diagnostic efficacy of each parameter for cervical cancer was evaluated by using the operating characteristic curve (ROC curve). Results the standard ADC of the observation group and the control group was 0.90 鹵0.15 脳 10 ~ (-1) ~ (-3) respectively. The slow ADC was 0.70 鹵0.12 脳 10 ~ (-3) 脳 10 ~ (-3) / s (n = 1.15 鹵0.23) 脳 10 ~ (-3) / s. The ADC was 0.97 鹵0.21) 脳 10 ~ (-1) mm ~ (-3) / s, and the fast ADC was 6.66 鹵2.02 脳 10 ~ (-3)). 5.30 鹵1.64) 脳 10 ~ (-3) / m ~ (-2) / s ~ (-1) F = 0.29 鹵0.09 鹵0.45 鹵0.11, respectively; The standard ADCand slow ADCF in the observation group were lower than those in the control group (P < 0.05). There was no significant difference in fast ADC between the two groups (P < 0.05). The area under the curve of fast ADC and f for diagnosis of cervical cancer was 0.79 ~ 0.86 ~ 0.32 ~ 0.84, respectively. Slow ADC was the largest. When the critical value was 0.89 脳 10 ~ (-3) mm ~ (-1) / s, the sensitivity of diagnosis of cervical cancer was 70 and the specificity was 90. Conclusion the IVIM related parameter standard ADC for cervical cancer patients. Slow ADC and f were decreased, and the above parameters were helpful for the diagnosis of cervical cancer.
【作者單位】： 武漢大學(xué)中南醫(yī)院;荊門(mén)市第一人民醫(yī)院;
【分類(lèi)號(hào)】：R445.2;R737.33
【正文快照】： 目前磁共振檢查廣泛用于宮頸癌的診斷,其中擴(kuò)散加權(quán)成像(DWI)在宮頸癌的診斷、分期以及預(yù)后評(píng)估方面均具有較高的應(yīng)用價(jià)值[1,2]。DWI中最常用的參數(shù)表觀擴(kuò)散系數(shù)(ADC)可在一定程度上反映組織內(nèi)水分子擴(kuò)散程度,但傳統(tǒng)單一指數(shù)模型具有一定局限性,例如毛細(xì)微循環(huán)無(wú)規(guī)律方向灌注

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 M. Sasaki;K. Yamada;Y. Watanabe;M. Matsui;M. Ida;S. Fujiwara;田鳳娟;趙峰;;不同平臺(tái)的絕對(duì)表觀擴(kuò)散系數(shù)值可能存在實(shí)質(zhì)性差異:一項(xiàng)多廠家、多機(jī)構(gòu)的比較研究[J];國(guó)際醫(yī)學(xué)放射學(xué)雜志;2009年01期

2 陳利華;陳永峰;張久權(quán);王文偉;夏云寶;王健;;表觀擴(kuò)散系數(shù)值在鑒別不同組織學(xué)類(lèi)型肺癌中的價(jià)值[J];中國(guó)醫(yī)學(xué)影像技術(shù);2012年08期

3 潘希敏;魏富鑫;黎規(guī)典;;表觀擴(kuò)散系數(shù)在子宮惡性腫瘤診斷中的應(yīng)用價(jià)值[J];臨床醫(yī)學(xué)工程;2013年10期

4 A.F.Halaweish;E.A.Hoffman;D.R.Thedens;M.K.Fuld;J.P.Sieren;E.J.R.van Beek;王霽g;;不吸煙者肺膨脹水平對(duì)超極化~3He表觀擴(kuò)散系數(shù)測(cè)量的影響[J];國(guó)際醫(yī)學(xué)放射學(xué)雜志;2013年05期

5 王霈;張輝;蘇晉生;張華華;武瑞鳳;郭娟;王俊波;秦江波;;正常婦女乳腺不同月經(jīng)周期表觀擴(kuò)散系數(shù)差異的初探[J];中國(guó)藥物與臨床;2009年01期

6 管s，

本文編號(hào)：1402170